Landmark trial

Postoperative stereotactic radiosurgery compared with whole brain radiotherapy for resected metastatic brain disease (NCCTG N107C/CEC·3): a multicentre, randomised, controlled, phase 3 trial

Brown PD, Ballman KV, Cerhan JH, et al. · Alliance / CCTG

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DoseLab summary

Phase 3 trial (NCCTG N107C/CEC.3) after resection of a brain metastasis: cavity SRS preserved cognition better than whole-brain radiotherapy, with no difference in survival. Citation checked against Crossref.

Why this is useful

The trial behind post-operative cavity SRS instead of whole-brain treatment.

Reference details

Title
Postoperative stereotactic radiosurgery compared with whole brain radiotherapy for resected metastatic brain disease (NCCTG N107C/CEC·3): a multicentre, randomised, controlled, phase 3 trial
Authors / organization
Brown PD, Ballman KV, Cerhan JH, et al. · Alliance / CCTG
Publication / protocol
Lancet Oncol. 2017;18(8):1049–1060
Version
Pending verification
Year
2017
DOI
10.1016/S1470-2045(17)30441-2
Disease sites
CNS / Brain
Topics
SRS, Post-operative, Brain metastases, Landmark trial
Fractionation context
Pending verification
Last reviewed by DoseLab
Pending verification

Cited on DoseLab