Observational study
Risk of ischemic heart disease in women after radiotherapy for breast cancer
Darby SC, Ewertz M, McGale P, et al.
DoseLab summary
Population-based case-control study relating mean heart dose to later major coronary events after breast radiotherapy. Citation as given in the eviQ reference list; not yet checked against the journal.
Why this is useful
The study most often quoted for why mean heart dose matters in breast radiotherapy — the reason every breast table here says to keep heart dose as low as reasonably achievable.
Reference details
- Title
- Risk of ischemic heart disease in women after radiotherapy for breast cancer
- Authors / organization
- Darby SC, Ewertz M, McGale P, et al.
- Publication / protocol
- N Engl J Med. 2013;368(11):987–998
- Version
- Pending verification
- Year
- 2013
- DOI
- Pending verification
- Disease sites
- Breast
- Topics
- Breast, Heart, Toxicity
- Fractionation context
- Pending verification
- Last reviewed by DoseLab
- Pending verification