Clinical resource

Anal definitive EBRT chemoradiation (eviQ ID 1860)

eviQ, Cancer Institute NSW

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DoseLab summary

Endorsed eviQ protocol for definitive chemoradiation of anal cancer with IMRT and a simultaneous integrated boost: 50.4 Gy in 28 fractions for non-bulky disease or 54 Gy in 30 fractions for bulky primary or nodal disease, with elective nodes at a lower dose level. Target volumes follow the AGITG contouring atlas. Its organs-at-risk table states that it is based on RTOG 0529 and QUANTEC. It stresses keeping overall treatment time short and avoiding treatment breaks.

Why this is useful

An anal cancer IMRT protocol whose organ table — bladder, genitalia, femoral heads, bone marrow and bowel — is based on RTOG 0529.

Reference details

Title
Anal definitive EBRT chemoradiation (eviQ ID 1860)
Authors / organization
eviQ, Cancer Institute NSW
Publication / protocol
eviQ Radiation Oncology protocol 1860
Version
v.8 — last reviewed 14 June 2024; review due 30 June 2027
Year
2024
DOI
Pending verification
Disease sites
GI
Topics
Anal canal, IMRT, SIB, Dose painting, Conventional fractionation, Dose Constraints, Protocols
Fractionation context
50.4 Gy / 28 fx or 54 Gy / 30 fx (SIB), elective nodes 40–45 Gy
Last reviewed by DoseLab
2026-09-29

Cited on DoseLab