Landmark trial
Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial
Nout RA, Smit VT, Putter H, et al. · Dutch Gynaecological Cancer Group
DoseLab summary
PORTEC-2 randomized women with high-intermediate risk endometrial cancer to vaginal brachytherapy or pelvic external beam radiotherapy after surgery. Vaginal brachytherapy gave similar vaginal control with fewer bowel side effects. Citation checked against Europe PMC.
Why this is useful
Why vaginal cuff brachytherapy alone is common for high-intermediate risk endometrial cancer.
Reference details
- Title
- Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial
- Authors / organization
- Nout RA, Smit VT, Putter H, et al. · Dutch Gynaecological Cancer Group
- Publication / protocol
- Lancet. 2010;375(9717):816–823
- Version
- Pending verification
- Year
- 2010
- DOI
- 10.1016/S0140-6736(09)62163-2
- Disease sites
- GYN
- Topics
- Endometrium, Brachytherapy, Vaginal cuff
- Fractionation context
- Pending verification
- Last reviewed by DoseLab
- Pending verification