Clinical resource

NRG Oncology Protocol Development Template for Radiation Therapy — Gastrointestinal Cancer: Anal Cancer

Yock A, Parker W, et al. · NRG Oncology Medical Physics Subcommittee / Radiation Oncology Committee

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DoseLab summary

The template NRG Oncology gives investigators for writing the radiation therapy section of an anal cancer trial. Its example text and values are based on RTOG 0529 and the ECOG-ACRIN DECREASE trial (EA2182), and are meant to be edited for each protocol. It covers immobilization (a supine "frog-leg" position is recommended), CT or PET/CT simulation, rigid registration of MRI and PET to the planning CT, standard structure names, dose compliance tables and planning priorities.

Why this is useful

How an NRG trial would write the radiation section for anal cancer: simulation, image fusion, standard structure names, compliance tables and planning priorities — a good model of a modern US protocol.

Reference details

Title
NRG Oncology Protocol Development Template for Radiation Therapy — Gastrointestinal Cancer: Anal Cancer
Authors / organization
Yock A, Parker W, et al. · NRG Oncology Medical Physics Subcommittee / Radiation Oncology Committee
Publication / protocol
NRG Oncology protocol template
Version
Version 2, 10 January 2025
Year
2025
DOI
Pending verification
Disease sites
GI
Topics
Anal canal, NRG, Protocols, Image registration, Simulation, Structure naming
Fractionation context
Example: 50.4–54 Gy (primary), 42–45 Gy (elective nodes), 28–30 fx
Last reviewed by DoseLab
2026-09-29

Cited on DoseLab