Clinical resource

NRG Oncology Protocol Development Template for Radiation Therapy — Gynecological Cancer: Cervix, Uterine Cervix

Lee YC, Benedict SH, Tsai P, Liang X, Padgett K, Portelance L · NRG Oncology Medical Physics Subcommittee / Radiation Oncology Committee

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DoseLab summary

The template NRG Oncology gives investigators for writing the radiation therapy section of a cervical cancer trial, covering external beam (photon, MR-linac and proton) and brachytherapy. It describes supine or prone setup, full- and empty-bladder simulation scans fused to build an internal target volume, diagnostic MRI and PET/CT fusion, standard structure names (including Spc_Bowel and BoneMarrow), example prescriptions, HDR point A and volume-directed (CTV_HR) brachytherapy, and per-protocol and variation-acceptable compliance criteria for both the external beam plan and the combined EBRT + brachytherapy dose. Its values are examples meant to be edited for each trial. DoseLab's cervix tables quote its per-protocol levels.

Why this is useful

A complete US-style radiation section for cervical cancer: simulation, fusion, structure names, EBRT organ goals and combined EBRT + brachytherapy limits in EQD2.

Reference details

Title
NRG Oncology Protocol Development Template for Radiation Therapy — Gynecological Cancer: Cervix, Uterine Cervix
Authors / organization
Lee YC, Benedict SH, Tsai P, Liang X, Padgett K, Portelance L · NRG Oncology Medical Physics Subcommittee / Radiation Oncology Committee
Publication / protocol
NRG Oncology protocol template
Version
Version 1, May 2024
Year
2024
DOI
Pending verification
Disease sites
GYN
Topics
Cervix, NRG, Protocols, Brachytherapy, Image registration, Simulation, Structure naming, Dose Constraints
Fractionation context
45–50.4 Gy / 25–28 fx pelvis ± nodal boost, then HDR, PDR or LDR brachytherapy
Last reviewed by DoseLab
2026-09-30

Cited on DoseLab