Landmark trial
International Atomic Energy Agency Randomized Phase III Study of Radiation Therapy in Elderly and/or Frail Patients With Newly Diagnosed Glioblastoma Multiforme
Roa W, Kepka L, Kumar N, et al. · IAEA
DoseLab summary
IAEA randomized trial in elderly and/or frail patients with glioblastoma comparing 25 Gy in 5 fractions with 40 Gy in 15 fractions; survival was similar. Citation checked against Crossref.
Why this is useful
The evidence for one-week treatment in older or frail patients.
Reference details
- Title
- International Atomic Energy Agency Randomized Phase III Study of Radiation Therapy in Elderly and/or Frail Patients With Newly Diagnosed Glioblastoma Multiforme
- Authors / organization
- Roa W, Kepka L, Kumar N, et al. · IAEA
- Publication / protocol
- J Clin Oncol. 2015;33(35):4145–4150
- Version
- Pending verification
- Year
- 2015
- DOI
- 10.1200/JCO.2015.62.6606
- Disease sites
- CNS / Brain
- Topics
- Glioma, Glioblastoma, Hypofractionation, Landmark trial
- Fractionation context
- 25 Gy / 5 fx vs 40 Gy / 15 fx
- Last reviewed by DoseLab
- Pending verification