Landmark trial
Stereotactic Body Radiation Therapy for Inoperable Early Stage Lung Cancer (RTOG 0236)
Timmerman R, Paulus R, Galvin J, et al. · Radiation Therapy Oncology Group (RTOG)
DoseLab summary
Phase 2 multicenter trial of SBRT for medically inoperable, early-stage, peripheral non-small cell lung cancer. The original normal-tissue limits written for this trial are reproduced and discussed in Timmerman 2022 (Table 1).
Why this is useful
The first cooperative-group trial of lung SBRT. Activating it required normal-tissue limits and plan construction and evaluation guidelines — the origin story told in Timmerman 2022.
Reference details
- Title
- Stereotactic Body Radiation Therapy for Inoperable Early Stage Lung Cancer (RTOG 0236)
- Authors / organization
- Timmerman R, Paulus R, Galvin J, et al. · Radiation Therapy Oncology Group (RTOG)
- Publication / protocol
- JAMA. 2010;303(11):1070–1076
- Version
- Pending verification
- Year
- 2010
- DOI
- Pending verification
- Disease sites
- Lung
- Topics
- SBRT, Landmark trial, RTOG, Peripheral tumors
- Fractionation context
- SBRT (3 fractions)
- Last reviewed by DoseLab
- Pending verification