Observational study
Dosimetric predictors of duodenal toxicity after intensity modulated radiation therapy for treatment of the para-aortic nodes in gynecologic cancer
Verma J, Sulman EP, Jhingran A, et al.
DoseLab summary
Review of 105 patients given para-aortic nodal IMRT for gynecologic cancers. A larger duodenal volume receiving 55 Gy predicted late duodenal toxicity; the authors suggest keeping V55 below 15 cm³. DoseLab read the abstract.
Why this is useful
The source of the duodenum V55 Gy <15 cc goal used in conventionally fractionated upper-abdominal plans.
Reference details
- Title
- Dosimetric predictors of duodenal toxicity after intensity modulated radiation therapy for treatment of the para-aortic nodes in gynecologic cancer
- Authors / organization
- Verma J, Sulman EP, Jhingran A, et al.
- Publication / protocol
- Int J Radiat Oncol Biol Phys. 2014;88(2):357–362
- Version
- Pending verification
- Year
- 2014
- DOI
- 10.1016/j.ijrobp.2013.09.053
- Disease sites
- GI, GYN
- Topics
- Duodenum, IMRT, Dose Constraints, Conventional fractionation
- Fractionation context
- 45–50.4 Gy with boost to 60–66 Gy
- Last reviewed by DoseLab
- 2026-09-29