CNS / Brain

High-grade glioma, radiosurgery, palliative whole brain and hippocampal-avoidance whole brain — setup, MRI fusion, targets, brain OARs and cited constraints.

Brain planning is a problem of small, critical structures packed around the target. The brainstem, optic chiasm, optic nerves and cochleae tolerate far less dose than most tumors need, and they often sit only millimeters away — so MRI fusion, careful contouring and a steep dose gradient carry much of the work.

The techniques range widely. A glioma is treated over three to six weeks to an infiltrative target defined on MRI. Radiosurgery gives a very high dose to one or more small metastases in one to five fractions. Palliative whole-brain treatment uses two lateral fields shaped to the skull base, while hippocampal-avoidance whole brain is an IMRT or VMAT plan built around an MRI-defined structure in the middle of the target. Each treatment page below has its own constraint table, quoted from a published protocol with the source behind every value.

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Treatment pages
Across CNS / brain
Organs at risk

CNS / Brain structures

Each organ page shows its CNS / brain dose constraints with sources, plus anatomy, why it matters and contouring resources.