Describes and validates a standardized CT-based method for delineating the brachial plexus, developed in patients treated with IMRT for head and neck cancer.
Brachial Plexus
Dose constraints
Lung SBRT
| Schedule | Constraint | Source |
|---|---|---|
| 30–34 Gy / 1 fx Peripheral | Max dose <15 Gy | TROG SAFRON II |
| 54 Gy / 3 fx Peripheral | Max dose <24 Gy | TROG CHISEL |
| 50 Gy / 5 fx Central | Max dose 32 Gy | RTOG 0813 |
| D3 cc <30 Gy | RTOG 0813 |
Quoted from eviQ 3389 and eviQ 4018, checked 2026-09-22. Full table with references →
Conventional / Hypofractionated Lung RT
| Schedule | Constraint | Source |
|---|---|---|
| 60 Gy / 30 fx ± concurrent chemotherapy | Max dose ≤66 Gy (EQD2) | eviQ 1871 |
Quoted from eviQ 1871, checked 2026-09-22. Full table with references →
Anatomy
A network of nerves formed from the ventral rami of C5–T1. It passes between the anterior and middle scalene muscles, over the first rib and under the clavicle into the axilla, traveling alongside the subclavian and then axillary vessels.
Function in the body
The nerves that run from the neck into the arm. They control the muscles of the shoulder, arm and hand and carry feeling back from them.
Why it matters
Injury causes brachial plexopathy — pain, weakness or numbness in the arm — which can be permanent. In lung, it matters most for apical (superior sulcus) tumors and for supraclavicular nodal targets. In SBRT tables it is treated as a serial structure with a point-dose limit. In head and neck treatment it lies next to the lower neck nodal levels (IV and V), so it is evaluated whenever the lower neck is treated; target coverage usually takes priority.
How to contour
The plexus is hard to see directly on CT, so standardized methods use nearby anatomy — the scalene muscles and the subclavian/axillary vessels — as guides. The Hall method (developed in head and neck patients) is the most widely used; the Kong thoracic atlas covers it for chest cases. Timmerman 2022 Tables 8–11 include a contouring instruction for the plexus as well. Sources commonly define the plexus per side — for example, Timmerman 2022 Table 1 names the ipsilateral plexus.
A thoracic organ-at-risk contouring atlas with discussion of dose limits, covering the lung, proximal bronchial tree, esophagus, spinal cord, ribs and brachial plexus. A published letter in response discusses esophageal delineation.
Further reading
- RTOG 0813 protocol — RTOG 0813 protocol — SBRT for centrally located NSCLC Source
- RTOG 0915 protocol — RTOG 0915 protocol — SBRT for peripheral stage I NSCLC Source
- Timmerman 2022 — A Story of Hypofractionation and the Table on the Wall Source