Landmark trial

Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: 5-year outcomes of the randomised, non-inferiority, phase 3 CHHiP trial

Dearnaley D, Syndikus I, Mossop H, et al.

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DoseLab summary

Randomized phase 3 non-inferiority trial of conventional versus moderately hypofractionated IMRT for localized prostate cancer. A correction to this article was also published.

Why this is useful

The trial that established 60 Gy in 20 fractions; its protocol's dose–volume constraints are the basis of the 20-fraction column.

Reference details

Title
Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: 5-year outcomes of the randomised, non-inferiority, phase 3 CHHiP trial
Authors / organization
Dearnaley D, Syndikus I, Mossop H, et al.
Publication / protocol
Lancet Oncol. 2016;17(8):1047–1060
Version
Pending verification
Year
2016
DOI
Pending verification
Disease sites
Prostate
Topics
Prostate, Hypofractionation, Landmark trial
Fractionation context
Moderate hypofractionation vs conventional
Last reviewed by DoseLab
Pending verification

Cited on DoseLab