NRG Oncology Protocol Development Template for Radiation Therapy — Lung: Standard Fractionation

The NRG Oncology template for the radiation section of a conventionally fractionated lung trial. Its imaging section allows PET/CT or MRI for structure definition but asks that the final contours be confirmed on the planning CT, follows AAPM TG-132 for deformable registration, and notes that PET can help separate tumor from atelectasis. For plan evaluation it defines the prescription as the dose covering 95% of the PTV, with a protocol-specific D99% requirement, and asks that any dose above 105% of the prescription fall within the PTV rather than in normal tissue outside it.

How an NRG trial would write the radiation section for conventionally fractionated lung radiotherapy, including imaging and fusion for target definition.