Consensus guideline

Use of normal tissue complication probability models in the clinic

Marks LB, Yorke ED, Jackson A, et al. · QUANTEC

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DoseLab summary

The QUANTEC overview paper, whose summary table gathers the approximate dose/volume/outcome data from each organ chapter. Its footnotes stress that the data are estimates from the literature, should be applied with caution, and largely do not reflect modern IMRT. DoseLab read the esophagus row (mean dose <34 Gy for grade ≥3 acute esophagitis, 5–20%, 3D-CRT) from the open-access manuscript, and the lung, heart, liver, kidney, stomach and small bowel rows used on the GI pages from the journal's full-text table.

Why this is useful

The QUANTEC summary table: one-page dose/volume/outcome estimates for each organ, with the endpoint and complication rate behind every limit.

Reference details

Title
Use of normal tissue complication probability models in the clinic
Authors / organization
Marks LB, Yorke ED, Jackson A, et al. · QUANTEC
Publication / protocol
Int J Radiat Oncol Biol Phys. 2010;76(3 Suppl):S10–S19
Version
Pending verification
Year
2010
DOI
Pending verification
Disease sites
Lung, Prostate, GI, Head & Neck, CNS / Brain, Breast
Topics
Dose Constraints, QUANTEC, Conventional fractionation
Fractionation context
Standard fractionation (1.8–2.0 Gy per fraction) unless noted
Last reviewed by DoseLab
2026-09-29

Cited on DoseLab