GI · Organ at risk

Stomach

Educational Summary

Dose constraints

Pancreas

ScheduleConstraintSource
50.4 Gy / 28 fx
45–54 Gy / 25–30 fx
Whole organ D100% <45 GyQUANTEC summary

Avoid hotspots.

Quoted from QUANTEC summary, checked 2026-09-29. Full table with references →

Liver SBRT

ScheduleConstraintSource
42–54 Gy / 3 fx
Liver metastases
D0.1 cc ≤22.2 GyUK SABR consensus 2022
D10 cc ≤16.5 GyUK SABR consensus 2022
27.5–60 Gy / 5 fx
HCC or metastases
D0.1 cc ≤33 Gy (optimal), ≤35 Gy (mandatory)UK SABR consensus 2022
D10 cc ≤25 GyUK SABR consensus 2022

Quoted from eviQ 4026, checked 2026-09-29. Full table with references →

Anatomy

The stomach lies in the left upper quadrant, from the gastroesophageal junction to the pylorus. Its size, shape and position change with filling, which is why upper GI simulations use fasting or a consistent small drink.

Function in the body

The stomach holds swallowed food and starts breaking it down with acid and enzymes.

Why it matters

The stomach is a hollow, serial-like organ: the concern is ulceration, bleeding or perforation from high dose to part of its wall. It limits dose for gastroesophageal junction, pancreas and left-lobe liver targets. In SBRT, small-volume hotspots (such as the dose to 0.1–0.5 cc) are the main limits; in conventional plans, protocols ask to avoid hotspots in the stomach, and one esophageal protocol asks planners using IMRT or VMAT to consider the dose to the greater curvature.

How to contour

Jabbour 2014:

  • Oral contrast is recommended to show the stomach wall.
  • Contour the stomach as one organ — cardia, fundus, body, antrum and pylorus.
  • The cardia begins below the gastroesophageal junction; the fundus is the highest part, against the left hemidiaphragm.

Timmerman 2022 (Tables 8–11, written for its SBRT dose tables): the entire stomach wall and its contents, from the gastroesophageal junction to the start of the duodenum at the pylorus.

Review articleSource Verified
A Story of Hypofractionation and the Table on the Wall
Timmerman R · UT Southwestern Medical Center · 2022

An editorial history of the UT Southwestern SABR constraint tables — often called the “Timmerman tables” — covering how they were developed and revised, and their relationship to AAPM TG-101 and NRG/RTOG protocols. Tables 2–11 separate serial tissues (listed with a volume, a volume max and a max point dose) from parallel tissues (listed with a critical volume and a critical-volume dose max). In Tables 2–7 a footnote defines “point” as ≤0.035 cm³; Tables 8–11 add a contouring-instructions column for each structure.

Further reading

  • QUANTEC summary — Use of normal tissue complication probability models in the clinic Source
  • UK SABR consensus 2022 — UK 2022 Consensus on Normal Tissue Dose-Volume Constraints for Oligometastatic, Primary Lung and Hepatocellular Carcinoma Stereotactic Ablative Radiotherapy Source
  • LARK (TROG 17.03) — Study protocol of the LARK (TROG 17.03) clinical trial: a phase II trial investigating the dosimetric impact of Liver Ablative Radiotherapy using Kilovoltage intrafraction monitoring Source

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