GI · Organ at risk

Femoral Heads

Educational Summary

Dose constraints

Rectum

ScheduleConstraintSource
45–50.4 Gy / 25–28 fx
Long course
V40 Gy <40%, V45 Gy <25%RTOG 0822
Max <50 GyRTOG 0822

Quoted from eviQ 1863, checked 2026-09-29. Full table with references →

Anal Canal

ScheduleConstraintSource
50.4–54 Gy / 28–30 fx
Dose-painted IMRT
V30 Gy <50%, V40 Gy <35%, V44 Gy <5%RTOG 0529, NRG anal RT template

Quoted from eviQ 1860, checked 2026-09-29. Full table with references →

Anatomy

The rounded upper ends of the femurs that sit in the acetabulum of the pelvis. Planning structures often include the femoral neck as well, down to about the level of the lesser trochanter.

Function in the body

The femoral head is the ball of the hip joint, carrying the body's weight from the pelvis to the leg.

Why it matters

The concern is femoral head necrosis or femoral neck fracture — rare with modern planning but serious. Lateral beams in older 3D techniques could deliver meaningful dose here; with IMRT and VMAT the limits are usually met easily, but they still need checking, especially when lateral arcs or beam angles concentrate dose through the hips.

In rectal and anal cancer the elective nodal volumes (internal and external iliac, and inguinal in anal cancer) sit close to the femoral heads and necks, so their limits are checked in every pelvic GI plan.

In gynecologic treatment the external iliac and (for vulvar cancer) inguinofemoral nodal volumes pass close to the femoral heads and necks. NRG's GYN templates write their limits as D15% plus a near-maximum (D0.03 cc).

How to contour

Sources draw quite different structures:

  • Gay 2012 (proximal femur): from the top of the ball of the femur down to the lowest level of the ischial tuberosities, including the trochanters. A bone threshold auto-contour helps, but edit it afterwards.
  • The NRG anal cancer template (femoral head): the femoral head excluding the femoral neck, with the bottom border at the lesser trochanter.
  • Timmerman 2022 (Tables 8–11, written for its SBRT dose tables): contour the right and left separately.

Because the volumes differ, a limit only makes sense on the structure it was written for.

Clinical resourceSource Verified
NRG Oncology Protocol Development Template for Radiation Therapy — Gastrointestinal Cancer: Anal Cancer
Yock A, Parker W, et al. · NRG Oncology Medical Physics Subcommittee / Radiation Oncology Committee · 2025

The template NRG Oncology gives investigators for writing the radiation therapy section of an anal cancer trial. Its example text and values are based on RTOG 0529 and the ECOG-ACRIN DECREASE trial (EA2182), and are meant to be edited for each protocol. It covers immobilization (a supine "frog-leg" position is recommended), CT or PET/CT simulation, rigid registration of MRI and PET to the planning CT, standard structure names, dose compliance tables and planning priorities.

Review articleSource Verified
A Story of Hypofractionation and the Table on the Wall
Timmerman R · UT Southwestern Medical Center · 2022

An editorial history of the UT Southwestern SABR constraint tables — often called the “Timmerman tables” — covering how they were developed and revised, and their relationship to AAPM TG-101 and NRG/RTOG protocols. Tables 2–11 separate serial tissues (listed with a volume, a volume max and a max point dose) from parallel tissues (listed with a critical volume and a critical-volume dose max). In Tables 2–7 a footnote defines “point” as ≤0.035 cm³; Tables 8–11 add a contouring-instructions column for each structure.

Further reading

  • QUANTEC — QUANTEC — Quantitative Analyses of Normal Tissue Effects in the Clinic Source
  • ENZARAD protocol — ENZARAD (ANZUP 1303): a randomised phase 3 trial of enzalutamide in androgen deprivation therapy with radiation therapy for high risk, clinically localised, prostate cancer Source
  • King 2012 — Long-term outcomes from a prospective trial of stereotactic body radiotherapy for low-risk prostate cancer Source
  • NRG cervix RT template — NRG Oncology Protocol Development Template for Radiation Therapy — Gynecological Cancer: Cervix, Uterine Cervix Source
  • NRG vulva RT template — NRG Oncology Protocol Development Template for Radiation Therapy — Gynecological Cancer: Vulva Cancer Source

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